Kolhe Lab | MCG Path

Kolhe Lab

Leading the Future of Molecular Diagnostics

Kohle Lab is delivering state-of-the-art, NCI-designated comprehensive genomic testing in oncology (MATCH), with expertise in validating emerging technologies for clinical use and advancing the field through Dr. Kolhe's leadership in scientific advisory roles and peer-reviewed publications.

Dr. Kolhe serves as Chair of the Department of Pathology, Edgar R. Pund Distinguished Chair in Pathology, Director of the Georgia Esoteric and Molecular Laboratory, Associate Dean for Translational Research at the Medical College of Georgia, and Associate Director for Genomics at the Georgia Cancer Center.

He has co-founded the Sequencing and Oncological Informatics Academic Team (SEQUOIA), an international consortium of clinical professionals employing TSO500. He is also a co-founder of the International Consortium for Optical Genome Mapping (ICOGM) centered on engaging the cytogenomic community's advancements in OGM.

PrecisionLab

PrecisionLab provides medical students with clinical research opportunities focused on uncovering genomic signatures that help classify cancer patients—an essential step in guiding personalized treatment strategies for clinicians. For those interested in these positions, please contact Dr. Ahluwalia.

Houman Qassab and Diana Danelia presented their research on "Immunogenomic Signature Associated with Never-Smokers with Non-Small Cell Lung Cancer (NSCLC)" at the Medical College of Georgia Research Day, 2024.

Andrea Smith presented "Adhesion-related Transcriptomic Changes and Their Clinical Significance in Colorectal Cancer" at the SECERS Conference in Savannah, 2024.

Carys Thompson presented "Adhesion-related Transcriptomic Changes and Their Clinical Significance in Colorectal Cancer" at the SECERS Conference in Savannah, 2024.

Mason Arbery highlighted "The Prognostic and Predictive Significance of Glutathione Metabolism in Colorectal Cancer" at the Medical College of Georgia Research Day, 2024.

Not pictured: Kalyani Ballur presented a study titled "Development of an LTBP3-related Gene Signature in Colorectal Cancer" at the College of American Pathologists Annual Meeting, 2023 and at the Georgia Cancer Center/University of Georgia Annual Retreat, 2023 (received the Best Poster Award).

Lab Staff

Ashis Mondal, PhD, MB(ASCP)CM

Lab Supervisor

Assistant Professor

Kimya Jones, MS, HT(ASCP)CM, QIHC(ASCP)CM

Lab Manager

Vishakha Vashisht, PhD, MB(ASCP)CM

Postdoctoral Fellow

Pankaj Ahluwalia, PhD

Assistant Research Scientist

Saloni Andhari, PhD

Postdoctoral Fellow

Ashutosh Vashisht, PhD, MB(ASCP)CM

Postdoctoral Fellow

Jana Woodall, MPH, CCRC

Pandemic Medicine Fellow

Aruna Bandi-Ganta, MSc

Data Coordinator

Featured publications

Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19

Clinical and molecular assessment of an onco‐immune signature with prognostic significance in patients with colorectal cancerColorectal cancer has a complex tumor microenvironment that also provides a unique opportunity for the molecular classification of these patients. In this study, we have used NanoString technology to...

Infections of the lung: a predictive, preventive and personalized perspective through the lens of evolution, the emergence of SARS-CoV-2 and its pathogenesis - EPMA Journal

Optical Genome Mapping and Single Nucleotide Polymorphism Microarray: An Integrated Approach for Investigating Products of Conception

Clinical Validation and Diagnostic Utility of Optical Genome Mapping in Prenatal Diagnostic Testing

High-Throughput Next-Generation Sequencing Respiratory Viral Panel: A Diagnostic and Epidemiologic Tool for SARS-CoV-2 and Other Viruses

Clinical Validation of a Sensitive Test for Saliva Collected in Healthcare and Community Settings with Pooling Utility for Severe Acute Respiratory Syndrome Coronavirus 2 Mass SurveillanceThe clinical performance of saliva compared with nasopharyngeal swabs (NPSs) has shown conflicting results in healthcare and community settings. In th…

Prognostic and therapeutic implications of extracellular matrix associated gene signature in renal clear cell carcinoma - Scientific Reports

Ethno‐demographic disparities in humoral responses to the COVID‐19 vaccine among healthcare workersJournal of Medical Virology is a clinical virology journal focused on the diagnosis, epidemiology, immunology and pathogenesis of human viral infections & diseases.

Infection and Immune Memory: Variables in Robust Protection by Vaccines Against SARS-CoV-2

Alteration in Nasopharyngeal Microbiota Profile in Aged Patients with COVID-19

SalivaSTAT: Direct-PCR and Pooling of Saliva Samples Collected in Healthcare and Community Setting for SARS-CoV-2 Mass Surveillance

Clinical validation of a multiplex PCR-based detection assay using saliva or nasopharyngeal samples for SARS-Cov-2, influenza A and B - Scientific Reports

Optical Genome Mapping: Integrating Structural Variations for Precise Homologous Recombination Deficiency Score Calculation

Guideline-Adherent Clinical Validation of a Comprehensive 170-Gene DNA/RNA Panel for Determination of Small Variants, Copy Number Variations, Splice Variants, and Fusions on a Next-Generation Sequencing Platform in the CLIA Setting

Natural Killer Cells and Dendritic Cells: Expanding Clinical Relevance in the Non-Small Cell Lung Cancer (NSCLC) Tumor Microenvironment

Immunogenomic Gene Signature of Cell-Death Associated Genes with Prognostic Implications in Lung Cancer

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